TBPH is one of two primary components in the novel brominated flame retardant, Firemaster 550 (Roberts et al. 2012, Springer et al. 2012, Fic et al. 2014). Widespread use of these novel flame retardants has lead to an increase in human exposure to this new family of chemicals and little research has been done on their chronic effects on human health (Springer et al. 2012). While TBPH is not thought to be an endocrine disrupting chemical, its primary metabolite is associated with both anti-estrogenic and anti-androgenic effects (Roberts et al. 2012). Exposure of pregnant female rats to TBMEHP, the primary metabolite, at a dose of 200 or 500 mg/kg lead to dose dependent increases in hypothyroidism, hepatotoxicity, and an increase in male fetus multinucleated germ cells associated with fetal testes toxicity (Springer et al. 2012).